It's tempting to embellish your achievements on your resume. The whole point is to put forward a representation of you that gets you hired. You're expected to put forward information that presents you in a positive light, but don't take it to the point of making up degrees and lying about what you've accomplished.
The Internet Knows Everything
Even if your potential employer doesn't do a full background check, they're likely to do a simple Google search on your name. If the information on your resume doesn't match what they find on Google, that will send up a red flag. And even if you pay a reputation management firm to try to push negative information down in the search results, the information is still out there. It's better to prepare responses to the negative information that show you learned from the situation.
Employees want employees they can trust. The job may involve handling money; it may involve handling valuable intellectual property. In every case, companies need to believe you'll be honest and treat their money and property respectfully. There's no worse way to prove you're honest enough for a job than lying about yourself before you're even hired.
You Set Yourself Up for Failure
If you manage to nab an interview, but don't have the skills and experience claimed on your resume, it's not likely to go well. Employers are likely to probe to verify you have the knowledge implied by acronyms and buzzwords, and if you threw them in just to get in the door, you won't make a good impression. If you somehow manage to actually get a job that requires the skills you claimed, you're not likely to succeed on the job.
You Can Get Fired
Don't think you're safe just because you got the job and you're managing to perform okay. You can get fired for lying whenever the company finds out about it.
You Hurt Yourself
Even if you fake your way through everything, get a job, and manage to succeed on it, you'll know it's all based on a lie. Protect your self-esteem and base your career on a solid foundation instead. If you think you need to lie about your accomplishments to get a job, there are other ways to buff your resume.
You can take training to get the skills you lack, or complete an academic program to earn that degree. You can prepare answers to questions about why you should be hired despite lacking a specific certification or skill. And you can network to meet and impress potential hiring managers in person, rather than meeting them as a piece of paper. It's far better for you in the long term if you take more time to find a job you're really suited for, based on your actual achievements than to lie to take a shortcut.